About me
I am a PostDoc at EPFL and the University Hospital Zürich, working with Charlotte Bunne and Andreas Wicki.
My interdisciplinary research advances personalized medicine by developing AI for spatial omics technologies that tackle diagnostic, therapeutic, and discovery tasks.
Previously, I completed my Ph.D. in Computer Science at ETH Zürich and the German Cancer Research Center (DKFZ), supervised by Joachim Buhmann and Paul Jäger.
🎓 Academic Education
- [PostDoc] Joint PostDoc in the AIMM Group at EPFL and the Department of Oncology at the University Hospital Zürich
- [Ph.D.] Computer Science Ph.D. in the ISE Group at ETH Zürich and the IML Group at the DKFZ
- [Ph.D.] DKFZ Fellowship recipient and completed the Helmholtz International Graduate School for Cancer Research
- [Ph.D.] External member of the IVIA Lab at ETH Zürich
- Master Thesis & Research Intern at ETH Zürich
- M.Sc. in Statistics at University of Geneva
- Intern at Microsoft
- B.Sc. in Economics at University of Mannheim
📑 Publications
Explainable AI-based analysis of human pancreas sections detects traits of type 2 diabetes
Lukas Klein, Sebastian Ziegler, Yanni Morgenroth, Eyke Schoeniger, Michele Solimena, Felicia Gerst, Robert Wagner, Fabian Isensee, Klaus Maier-Hein, Paul F. Jaeger
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Navigating the Maze of Explainable AI: A Systematic Approach to Evaluating Methods and Metrics
Lukas Klein, Carsten Lueth, Udo Schlegel, Till Bungert, Mennatallah El-Assady, Paul F.Jaeger
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Enhancing predictive imaging biomarker discovery through treatment effect analysis
Shuhan Xiao, Lukas Klein, Paul F. Jaeger, Jens Petersen, Klaus Maier-Hein
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Why context matters in VQA and Reasoning: Semantic interventions for VLM input modalities
Kenza Amara*, Lukas Klein*, Carsten Lüth, Paul Jäger, Hendrik Strobelt, Mennatallah El-Assady
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Interactive Semantic Interventions for VLMs: A Human-in-the-Loop Investigation of VLM Failure
Lukas Klein*, Kenza Amara*, Carsten T. Lüth*, Antonio Foncubierta-Rodríguez, Hendrik Strobelt, Mennatallah El-Assady, Paul F. Jaeger
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Explainable AI-based analysis of human pancreas sections detects traits of type 2 diabetes
Lukas Klein, Sebastian Ziegler, Yanni Morgenroth, Eyke Schoeniger, Michele Solimena, Felicia Gerst, Robert Wagner, Fabian Isensee, Klaus Maier-Hein, Paul F. Jaeger
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Discovering Process Dynamic for Scalable Perovskite Solar Cell Manufacturing with Explainable AI
Lukas Klein, Sebastian Ziegler, Felix Laufer, Charlotte Debus, Markus Götz, Klaus Maier-Hein, Ulrich
W. Paetzold, Fabian Isensee, Paul F. Jaeger
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Understanding Solar Cell Manufacturing with Explainable AI
Lukas Klein, Sebastian Ziegler, Felix Laufer, Charlotte Debus, Markus Götz, Klaus Maier-Hein, Ulrich
W. Paetzold, Fabian Isensee, Paul F. Jaeger
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Semi-supervised automated Gleason Grading on WSI
Maximilian Fischer, Lars Krämer, Sebastian Ziegler, Lukas Klein, Paul F. Jaeger, Marco Molden, Peter Neher, Fabian Isensee, Klaus Maier-Hein
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Navigating the Pitfalls of Active Learning Evaluation: A Systematic Framework for Meaningful Performance Assessment
Carsten T. Lüth, Till J. Bungert, Lukas Klein, Paul F. Jaeger
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A Call to Reflect on Evaluation Practices for Failure Detection in Image Classification
Paul F. Jaeger, Carsten T. Lueth, Lukas Klein, Till J. Bungert
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From Correlation to Causation: Formalizing Interpretable Machine Learning as a Statistical Process
Lukas Klein, Mennatallah El-Assady, Paul F Jaeger
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Improving Explainability of Disentangled Representations using Multipath-Attribution Mappings
Lukas Klein, João B. S. Carvalho, Mennatallah El-Assady, Paolo Penna, Joachim M. Buhmann, Paul F Jaeger
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